Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 8/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554474 | 0.86 | PDGFRB (0.52) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL2063193 | 0.86 | PDGFRB (0.52) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL31554584 | 0.86 | PDPK1 (0.54) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL19645711 | 0.85 | PDGFRB (0.53) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL12335689 | 0.84 | PDGFRB (0.50) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL20143871 | 0.84 | PDPK1 (0.46) | PDPK1EGFRKDM4EKDRSRC | |
| SCHEMBL15263519 | 0.83 | SRC (0.61) | PDGFRBPDGFRAEGFRKDRSRC | |
| SCHEMBL5452461 | 0.83 | EGFR (0.49) | PDGFRBPDGFRAPDPK1KDM1AIRAK1 | |
| SCHEMBL1893875 | 0.83 | SRC (0.61) | PDGFRBPDGFRAEGFRKDRSRC | |
| SCHEMBL5929650 | 0.83 | EGFR (0.53) | PDGFRBPDGFRAPDPK1KDM1AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393641-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | OXFORD FINANCE LLC | 2021-12-23 | — | — | US | disclosed |
| US-9827248-B2 | Therapeutic compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | WYETH (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393641-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | MUC1, CFTR, SLC26A4 | PDGFRB 2819/4885PDGFRA 3408/4885PDPK1 3891/4885 |
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | QPCT, RECQL, CBR3 | PDGFRB 1994/4885PDGFRA 1687/4885PDPK1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.