Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556648 | 0.91 | MAPT (0.40) | JAK2JAK1HPGDSGPR119MAPT | |
| SCHEMBL31556718 | 0.86 | TSHR (0.36) | USP30KDM1AGPR119MAPTMEN1 | |
| SCHEMBL31556669 | 0.85 | TSHR (0.36) | USP30KDM1AGPR119MAPTMEN1 | |
| SCHEMBL31556631 | 0.81 | TSHR (0.32) | JAK1ALDH1A1 | |
| SCHEMBL31556639 | 0.81 | TSHR (0.32) | JAK1ALDH1A1 | |
| SCHEMBL31556672 | 0.79 | ALDH1A1 (0.44) | USP30MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31556686 | 0.78 | CRBN (0.45) | JAK2JAK1BRD4 | |
| SCHEMBL31556585 | 0.77 | MPO (0.32) | PRMT5WDR77HTR6 | |
| SCHEMBL31556650 | 0.77 | TSHR (0.34) | JAK1USP30MAPTMEN1ALDH1A1 | |
| SCHEMBL31556524 | 0.77 | SLC6A2 (0.37) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |