Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478373 | 0.79 | HTR6 (0.51) | HTR6ACHEPARP1CHUKFEN1 | |
| SCHEMBL29642993 | 0.70 | ACHE (0.78) | ACHEPARP1CHUKFEN1KDM4E | |
| SCHEMBL972999 | 0.70 | ACHE (0.78) | ACHEPARP1CHUKFEN1KDM4E | |
| Trifluoroacetic Acid SCHEMBL23452232 | 0.69 | HTR6 (0.42) | HTR6ACHEPARP1CHUKFEN1 | |
| SCHEMBL4753505 | 0.65 | KDM5A (0.57) | PARP1 | |
| SCHEMBL13708855 | 0.65 | PARP1 (0.54) | ACHEPARP1FEN1KDM4E | |
| SCHEMBL3115940 | 0.64 | AURKA (0.48) | ACHEPARP1CHUKAURKAMAPT | |
| SCHEMBL31875233 | 0.64 | CACNA1H (0.44) | HTR6ACHEIDO1AOC1AOC3 | |
| SCHEMBL4072911 | 0.64 | CACNA1H (0.44) | HTR6ACHEIDO1AOC1AOC3 | |
| SCHEMBL30619662 | 0.63 | HTR6 (0.68) | HTR6ACHEKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |