Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560740 | 0.86 | HSD11B1 (0.42) | NPSR1OPRM1SIGMAR1CYP2D6KMT2A | |
| SCHEMBL31560753 | 0.86 | HSD11B1 (0.42) | NPSR1OPRM1SIGMAR1CYP2D6KMT2A | |
| SCHEMBL31560632 | 0.85 | NPSR1 (0.36) | NPSR1OPRM1SIGMAR1CYP2D6ALDH1A1 | |
| SCHEMBL31560620 | 0.84 | HDAC4 (0.41) | NPSR1OPRM1SIGMAR1CYP2D6ALDH1A1 | |
| SCHEMBL31560561 | 0.84 | HDAC4 (0.41) | NPSR1OPRM1SIGMAR1CYP2D6ALDH1A1 | |
| SCHEMBL31560498 | 0.84 | HDAC4 (0.41) | NPSR1OPRM1SIGMAR1CYP2D6ALDH1A1 | |
| SCHEMBL31560478 | 0.84 | ENPP2 (0.41) | OPRM1SIGMAR1CYP2D6ALDH1A1HDAC4 | |
| SCHEMBL31560629 | 0.84 | ENPP2 (0.41) | OPRM1SIGMAR1CYP2D6ALDH1A1HDAC4 | |
| SCHEMBL31560493 | 0.81 | HDAC4 (0.43) | OPRM1ALDH1A1KMT2AHDAC4LMNA | |
| SCHEMBL31560734 | 0.79 | HDAC4 (0.41) | CYP2D6ALDH1A1KMT2AHDAC4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | claimed |
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |