⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424703 | 0.66 | AOC3 (0.31) | — | |
| SCHEMBL15921926 | 0.65 | — | — | |
| SCHEMBL6142485 | 0.62 | — | — | |
| SCHEMBL30413685 | 0.62 | MEN1 (0.31) | — | |
| SCHEMBL31562324 | 0.62 | — | — | |
| SCHEMBL524225 | 0.62 | DGAT1 (0.34) | — | |
| SCHEMBL11017806 | 0.61 | TRPA1 (0.34) | — | |
| SCHEMBL28177103 | 0.61 | — | — | |
| SCHEMBL4599567 | 0.59 | KDM4A (0.32) | — | |
| SCHEMBL19892598 | 0.59 | HDAC6 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289789-A1 | REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. | 2025-09-18 | — | — | US | disclosed |
| WO-2025090658-A2 | REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-05-01 | — | — | WO | disclosed |