Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31564729 | 1.00 | EPHX2 (0.48) | EPHX2CTSKBTKMTNR1AMTNR1B | |
| SCHEMBL23519713 | 0.91 | EPHX2 (0.52) | EPHX2CTSKBTKDRD2KDM1A | |
| SCHEMBL29565539 | 0.82 | MTNR1A (0.66) | EPHX2BTKMTNR1AMTNR1BDRD2 | |
| SCHEMBL3682479 | 0.82 | MTNR1A (0.66) | EPHX2BTKMTNR1AMTNR1BDRD2 | |
| SCHEMBL5677299 | 0.81 | CA1 (0.64) | EPHX2BTKMTNR1AMTNR1BDRD2 | |
| SCHEMBL9136687 | 0.81 | CA1 (0.64) | EPHX2BTKMTNR1AMTNR1BDRD2 | |
| SCHEMBL7399411 | 0.81 | CA1 (0.64) | EPHX2CTSKMTNR1AMTNR1BDRD2 | |
| SCHEMBL5722246 | 0.81 | CA1 (0.64) | EPHX2BTKMTNR1AMTNR1BDRD2 | |
| SCHEMBL31564068 | 0.80 | EPHX2 (0.49) | EPHX2CTSKBTKMTNR1AMTNR1B | |
| SCHEMBL31563951 | 0.80 | EPHX2 (0.49) | EPHX2CTSKBTKMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025097104-A1 | THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2025-05-08 | — | — | WO | disclosed |