SCHEMBL315658

SCHEMBL315658

COS(=O)(=S)OC(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
LMNA P02545 2/20 0.47
F2 P00734 1/20 0.47
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC6A3 Q01959 2/20 0.41
KMT2A Q03164 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 3/20 0.40
RAB9A P51151 2/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17768681 0.79 LMNA (0.52) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL9405232 0.76 LMNA (0.49) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL1020413 0.76 TSHR (0.56) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL1315543 0.76 LMNA (0.58) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL29218973 0.76 LMNA (0.48) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL19439036 0.76 LMNA (0.48) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL27668297 0.75 TSHR (0.54) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL27647867 0.75 TSHR (0.54) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL4818821 0.74 LMNA (0.56) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL11150957 0.74 TSHR (0.58) TSHRLMNAF2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2216351-B2 Water-swellable copolymers and articles and coating made therefrom COVIDIEN LP (US) 2016-05-18 EP disclosed
US-8829129-B2 Water-swellable copolymers and articles and coatings made therefrom COVIDIEN LP (US) 2014-09-09 US disclosed
EP-2202250-B1 Water-swellable copolymers and articles and coating made therefrom COVIDIEN LP (US) 2013-10-09 EP disclosed
EP-2143740-B1 Water-swellable copolymers and articles and coating made therefrom COVIDIEN LP (US) 2013-06-19 EP disclosed
EP-2216351-B1 Water-swellable copolymers and articles and coating made therefrom TYCO HEALTHCARE (US) 2012-11-07 EP disclosed
US-20120125346-A1 ENDOTRACHEAL CUFF AND TECHNIQUE FOR USING THE SAME NELLCOR PURITAN BENNETT LLC (US) 2012-05-24 US disclosed
US-20120065676-A1 Water-Swellable Copolymers and Articles and Coatings Made Therefrom TYCO HEALTHCARE GROUP LP (US) 2012-03-15 US disclosed
EP-1778752-B1 WATER-SWELLABLE COPOLYMERS AND ARTICLES AND COATING MADE THEREFROM TYCO HEALTHCARE (US) 2012-02-15 EP disclosed
US-8092492-B2 Water-swellable copolymers and articles and coatings made therefrom TYCO HEALTHCARE GROUP LP (US) 2012-01-10 US disclosed
US-8083771-B2 Water-swellable copolymers and articles and coatings made therefrom TYCO HEALTHCARE GROUP LP (US) 2011-12-27 US disclosed
EP-2216351-A1 Water-swellable copolymers and articles and coating made therefrom Tyco Healthcare Group LP (US) 2010-08-11 EP disclosed
EP-2202250-A2 Water-swellable copolymers and articles and coating made therefrom Tyco Healthcare Group LP (US) 2010-06-30 EP disclosed
EP-2143740-A2 Water-swellable copolymers and articles and coating made therefrom TYCO HEALTHCARE GROUP LP (US) 2010-01-13 EP disclosed
EP-2131883-A2 ENDOTRACHEAL CUFF AND TECHNIQUE FOR USING THE SAME NELLCOR PURITAN BENNETT LLC (US) 2009-12-16 EP disclosed
WO-2008109009-A2 ENDOTRACHEAL CUFF AND TECHNIQUE FOR USING THE SAME NELLCOR PURITAN BENNETT LLC (US) 2008-09-12 WO disclosed
US-20080215034-A1 Endotracheal cuff and technique for using the same NELLCOR PURITAN BENNETT LLC 2008-09-04 US disclosed
EP-1778752-A4 WATER-SWELLABLE COPOLYMERS AND ARTICLES AND COATING MADE THEREFROM TYCO HEALTHCARE (US) 2008-05-14 EP disclosed
US-20080064839-A1 Formed from 3-sulfopropyl acrylate potassium salt, sodium acrylate, N-(tris(hydroxyl methyl)methyl)acrylamide, and 2-acrylamideo-2-methyl-1-propane sulfonic acid as monomers; sutures; surgical staples COVIDIEN LP 2008-03-13 US disclosed
EP-1778752-A1 WATER-SWELLABLE COPOLYMERS AND ARTICLES AND COATING MADE THEREFROM TYCO HEALTHCARE GROUP LP (US) 2007-05-02 EP disclosed
WO-2006023486-A1 WATER-SWELLABLE COPOLYMERS AND ARTICLES AND COATING MADE THEREFROM TYCO HEALTHCARE GROUP, LP (US) 2006-03-02 WO disclosed