Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234524 | 0.79 | LMNA (0.53) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL29218973 | 0.78 | LMNA (0.48) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL19439036 | 0.78 | LMNA (0.48) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL17768681 | 0.77 | LMNA (0.52) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL315658 | 0.76 | TSHR (0.53) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL28310222 | 0.75 | LMNA (0.53) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL1020413 | 0.75 | TSHR (0.56) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL1315543 | 0.74 | LMNA (0.58) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL2833087 | 0.74 | LMNA (0.47) | LMNATSHRF2TDP1MAPK1 | |
| SCHEMBL3018655 | 0.73 | F2 (0.52) | LMNATSHRF2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263556-B1 | A process for the preparation of saline derivatives of mercaptoethansulfonic acid | SCHERING SPA (IT) | 1994-01-05 | — | — | EP | claimed |
| US-4939291-A | Process for the preparation of mercaptoethansulfonic acid and sodium salt thereof | SCHERING SPA (IT) | 1990-07-03 | — | — | US | claimed |
| EP-0263556-B1 | A process for the preparation of saline derivatives of mercaptoethansulfonic acid | SCHERING SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| EP-0263556-A2 | A process for the preparation of saline derivatives of mercaptoethansulfonic acid | Schering Spa (IT) | 1988-04-13 | — | — | EP | disclosed |