Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31565962 | 0.90 | S1PR1 (0.50) | ALDH1A1RAB9APKMESR1ESR2 | |
| SCHEMBL31565916 | 0.90 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1NPC1RAB9APKM | |
| SCHEMBL31565894 | 0.90 | NPC1 (0.44) | ALDH1A1L3MBTL1NPC1RAB9APKM | |
| SCHEMBL31566058 | 0.87 | ESR1 (0.45) | ALDH1A1L3MBTL1ESR1ESR2LIPE | |
| SCHEMBL31565889 | 0.85 | ESR1 (0.47) | ALDH1A1L3MBTL1ESR1ESR2LIPE | |
| SCHEMBL31565830 | 0.85 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1RAB9AESR1ESR2 | |
| SCHEMBL31565831 | 0.85 | ESR1 (0.43) | ALDH1A1ESR1ESR2LIPEGHSR | |
| SCHEMBL31566054 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPC1RAB9AESR1 | |
| SCHEMBL31566040 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPC1RAB9AESR1 | |
| SCHEMBL25968671 | 0.85 | ESR1 (0.43) | ALDH1A1ESR1ESR2LIPEGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129028-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129028-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | YAP1, YES1, LATS1 | ALDH1A1 2760/4885L3MBTL1 1076/4885NPC1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.