SCHEMBL31566400

SCHEMBL31566400

CC(C)(C)[Si](C)(C)OC[C@H](O)c1ccc(F)cn1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
APLNR P35414 6/20 0.40
GRIN2B Q13224 12/20 0.34
GRIN1 Q05586 8/20 0.34
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26743081 1.00 APLNR (0.40) APLNRGRIN2BGRIN1ADRB2ADRB1
SCHEMBL24707461 0.87 APLNR (0.39) APLNRGRIN2BGRIN1
SCHEMBL29108371 0.83 BRD4 (0.36) APLNRGRIN2B
SCHEMBL29108146 0.83 BRD4 (0.36) APLNRGRIN2B
SCHEMBL29108150 0.83 BRD4 (0.36) APLNRGRIN2B
SCHEMBL13316649 0.83 APLNR (0.34) APLNR
SCHEMBL26621129 0.82 APLNR (0.33) APLNR
SCHEMBL1154910 0.79 AOC3 (0.42) GRIN2BGRIN1ADRB2ADRB1ADRB3
SCHEMBL3923781 0.79 APLNR (0.45) APLNRGRIN2BGRIN1
SCHEMBL31501546 0.78 APLNR (0.40) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118081-A Novel heterocyclic compound 首药控股(北京)股份有限公司 2025-06-10 CN disclosed
WO-2025034912-A9 COMPOUNDS FOR FGFR INHIBITION COGENT BIOSCIENCES, INC. (US) 2025-04-24 WO disclosed