Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568457 | 0.80 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2TP53RAB9AHPGD | |
| SCHEMBL22469762 | 0.80 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2TP53RAB9AHPGD | |
| SCHEMBL8370605 | 0.80 | HIF1A (0.50) | MRGPRX4SMN1; SMN2RAB9AHPGDLIPE | |
| SCHEMBL8370602 | 0.80 | HIF1A (0.50) | MRGPRX4SMN1; SMN2RAB9AHPGDLIPE | |
| SCHEMBL6743790 | 0.79 | MRGPRX4 (0.71) | MRGPRX4SMN1; SMN2HTTRAB9AHPGD | |
| SCHEMBL31568500 | 0.78 | MRGPRX4 (0.62) | MRGPRX4TP53HTTHPGDLIPE | |
| SCHEMBL3945751 | 0.74 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2RAB9AHPGDGLA | |
| SCHEMBL7535658 | 0.74 | MRGPRX4 (0.43) | MRGPRX4SMN1; SMN2RAB9AHPGDLIPE | |
| SCHEMBL8942464 | 0.73 | MRGPRX4 (0.66) | MRGPRX4SMN1; SMN2RAB9AHPGDGLA | |
| SCHEMBL10985263 | 0.72 | RAB9A (0.70) | MRGPRX4SMN1; SMN2HTTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939288-B | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2025-04-25 | — | — | CN | disclosed |