Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421429 | 0.87 | SMN1; SMN2 (0.65) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8637639 | 0.85 | RAB9A (0.55) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22469762 | 0.84 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2RAB9AHPGDKMT2A | |
| SCHEMBL31568457 | 0.84 | MRGPRX4 (1.00) | MRGPRX4SMN1; SMN2RAB9AHPGDKMT2A | |
| SCHEMBL8431628 | 0.84 | MRGPRX4 (0.52) | MRGPRX4CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4160021 | 0.84 | MRGPRX4 (0.52) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4284174 | 0.84 | MRGPRX4 (0.52) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27382834 | 0.83 | RAB9A (0.59) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7916623 | 0.82 | MRGPRX4 (0.51) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30104807 | 0.82 | MRGPRX4 (0.51) | MRGPRX4SMN1; SMN2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1335903-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | MRGPRX4 1467/4885SMN1; SMN2 4597/4885CYP1A2 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.