SCHEMBL31569027

SCHEMBL31569027

CC1CN(C(=O)c2nc3cccc(Cl)c3[nH]2)Cc2cnc(C(F)(F)F)n21

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 20/20 0.46
PDK1 Q15118 18/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569406 1.00 PDK2 (0.46) PDK2PDK1
SCHEMBL31569272 0.90 PDK2 (0.46) PDK2PDK1
SCHEMBL31569439 0.90 PDK2 (0.46) PDK2PDK1
SCHEMBL31569148 0.89 PDK2 (0.46) PDK2PDK1
SCHEMBL31569529 0.86 PDK2 (0.38) PDK2PDK1
SCHEMBL31568955 0.86 PDK2 (0.38) PDK2PDK1
SCHEMBL31569289 0.86 PDK2 (0.38) PDK2PDK1
SCHEMBL31569372 0.84 P2RX7 (0.39) PDK2PDK1
SCHEMBL31569549 0.84 P2RX7 (0.39) PDK2PDK1
SCHEMBL31569137 0.82 PDK2 (0.42) PDK2PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217213-A2 COMPOSITIONS AND METHODS FOR TREATING RETINITIS PIGMENTOSA OCTANT, INC. (US) 2025-10-16 WO disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed