SCHEMBL31569372

SCHEMBL31569372

CC1Cn2c(cnc2C(F)(F)F)CN1C(=O)c1nc2cccc(Cl)c2[nH]1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 17/20 0.39
PARP1 P09874 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
PARP3 Q9Y6F1 1/20 0.34
PDK2 Q15119 2/20 0.34
PDK1 Q15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569549 1.00 P2RX7 (0.39) P2RX7PARP1PARP2PARP3PDK2
SCHEMBL31569173 0.85 P2RX7 (0.39) P2RX7
SCHEMBL31569544 0.85 PDK1 (0.38) P2RX7PDK2PDK1
SCHEMBL31568958 0.85 P2RX7 (0.38) P2RX7PARP1PARP2PARP3
SCHEMBL31569466 0.85 P2RX7 (0.38) P2RX7PARP1PARP2PARP3
SCHEMBL31569027 0.84 PDK2 (0.46) PDK2PDK1
SCHEMBL31569406 0.84 PDK2 (0.46) PDK2PDK1
SCHEMBL31569509 0.82 TACR3 (0.39) P2RX7
SCHEMBL31569497 0.82 P2RX7 (0.34) P2RX7PDK2PDK1
SCHEMBL31569259 0.80 P2RX7 (0.35) P2RX7PDK2PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217213-A2 COMPOSITIONS AND METHODS FOR TREATING RETINITIS PIGMENTOSA OCTANT, INC. (US) 2025-10-16 WO disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed