SCHEMBL31569039

SCHEMBL31569039

C=C(OCC)c1c(Cl)ccnc1CCNC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
HPGD P15428 3/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NQO2 P16083 1/20 0.40
STK17B O94768 1/20 0.40
STK17A Q9UEE5 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HTT P42858 2/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
XBP1 P17861 1/20 0.39
HSD17B10 Q99714 1/20 0.39
AAK1 Q2M2I8 1/20 0.38
KDM4E B2RXH2 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28878071 0.80 ATR (0.46) LMNAHPGDGAATSHRMEN1
SCHEMBL31569482 0.78 STK17B (0.46) LMNAHPGDGAATSHRMEN1
SCHEMBL31569008 0.75 NQO2 (0.39) NQO2STK17BSTK17AALDH1A1HTT
SCHEMBL25056476 0.73 KDM4E (0.45) MEN1KMT2ANQO2ALDH1A1HTT
SCHEMBL5592422 0.73 NQO2 (0.47) NQO2ALDH1A1HTTNPSR1KDM4E
SCHEMBL30564599 0.72 ATR (0.39) GAAALDH1A1AAK1CA12CA1
SCHEMBL31579768 0.72 NQO2 (0.41) LMNAHPGDTSHRMEN1KMT2A
SCHEMBL31569447 0.72 LMNA (0.41) LMNAHPGDGAATSHRMEN1
SCHEMBL3081832 0.72 KDM4E (0.44) LMNAHPGDGAAMEN1KMT2A
SCHEMBL31569411 0.71 KDM4E (0.42) LMNAHPGDGAATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D LMNA 3152/4885HPGD 3251/4885GAA 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.