SCHEMBL31569488

SCHEMBL31569488

C[C@@H]1Cn2c(cnc2C(F)(F)F)CN1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 18/20 0.33
PDK2 Q15119 18/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569170 1.00 PDK1 (0.33) PDK1PDK2
SCHEMBL31569454 1.00 PDK1 (0.33) PDK1PDK2
Hydrochloric Acid SCHEMBL34469191 0.80
SCHEMBL5232115 0.71 DPP4 (0.33)
SCHEMBL31177343 0.71 DPP4 (0.33)
SCHEMBL31568988 0.69
SCHEMBL31568966 0.68 PDK1 (0.33) PDK1PDK2
SCHEMBL31569146 0.67 HTR2A (0.33) PDK1PDK2
Hydrochloric Acid SCHEMBL16145625 0.65 TACR3 (0.32)
SCHEMBL24711537 0.62 PDK2 (0.33) PDK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D PDK1 4522/4885PDK2 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.