Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 5/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569995 | 0.92 | TP53 (0.51) | GPR119TP53BACE1TBK1AKR1B1 | |
| SCHEMBL9963101 | 0.85 | CHRM2 (0.50) | PIK3CAGPR119TP53TBK1CHRM2 | |
| SCHEMBL25400235 | 0.82 | PIK3CA (0.51) | PIK3CABACE1 | |
| SCHEMBL23932501 | 0.80 | NAMPT (0.46) | GPR119TP53TBK1 | |
| SCHEMBL29891575 | 0.78 | GPR119 (0.48) | GPR119TP53 | |
| SCHEMBL23411511 | 0.78 | GPR119 (0.47) | PIK3CAGPR119BACE1 | |
| SCHEMBL29891529 | 0.78 | GPR119 (0.47) | PIK3CAGPR119BACE1 | |
| SCHEMBL14157426 | 0.78 | GPR119 (0.48) | GPR119TP53 | |
| SCHEMBL31569595 | 0.78 | DDB1 (0.55) | PIK3CAGPR119 | |
| SCHEMBL29437047 | 0.78 | ALDH1A1 (0.48) | PIK3CAGPR119BACE1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101588-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |