SCHEMBL31573219

SCHEMBL31573219

CC(C)(C)OC(=O)N1C[C@H](OC(F)(F)F)C[C@H]1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.39
▸ UCHL1 P09936 1/20 0.38
▸ NR1H2 P55055 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ CHRM3 P20309 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ HTRA1 Q92743 1/20 0.34
▸ MCL1 Q07820 3/20 0.33
▸ RORC P51449 1/20 0.33
▸ JAK2 O60674 1/20 0.32
▸ JAK1 P23458 1/20 0.32
▸ HSD11B1 P28845 1/20 0.32
▸ BTK Q06187 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30536040 0.90 HSD17B10 (0.41) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL18577435 0.90 HSD17B10 (0.41) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL7298158 0.90 HSD17B10 (0.41) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL29015380 0.90 HSD17B10 (0.41) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL29015384 0.90 HSD17B10 (0.41) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL31573201 0.89 UCHL1 (0.36) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL31573211 0.86 P2RX3 (0.39) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL1270226 0.84 UCHL1 (0.49) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL92869 0.84 UCHL1 (0.49) HSD17B10UCHL1NR1H2CYP1A2POLB
SCHEMBL5480506 0.84 UCHL1 (0.49) HSD17B10UCHL1NR1H2CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096855-A1 DEGRADERS AND USES THEREOF KUMQUAT BIOSCIENCES INC. (US) 2025-05-08 — — WO disclosed
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