Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901450 | 1.00 | PKM (0.42) | PKMP2RX7IDO1AGXTKMT2A | |
| SCHEMBL29814990 | 0.83 | PKM (0.40) | PKMP2RX7IDO1AGXTKMT2A | |
| SCHEMBL3712167 | 0.83 | PKM (0.40) | PKMP2RX7IDO1AGXTKMT2A | |
| SCHEMBL458270 | 0.82 | PKM (0.38) | PKMIDO1AGXTKMT2AMEN1 | |
| SCHEMBL30227514 | 0.82 | PKM (0.38) | PKMIDO1AGXTKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL28943169 | 0.80 | PKM (0.37) | PKMIDO1AGXTKMT2AMEN1 | |
| SCHEMBL3637969 | 0.79 | CA2 (0.46) | PKMP2RX7IDO1AGXTKMT2A | |
| SCHEMBL30817945 | 0.79 | CA2 (0.46) | PKMP2RX7IDO1AGXTKMT2A | |
| SCHEMBL596489 | 0.79 | KMT2A (0.37) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL29494112 | 0.79 | PKM (0.39) | PKMP2RX7IDO1AGXTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096751-A1 | MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE | ESPERION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |