SCHEMBL31574483

SCHEMBL31574483

O=C(O)c1cccc(N2N=C(c3ccc(Cl)cc3)CC2c2ccc3nccnc3c2)c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
NPSR1 Q6W5P4 1/20 0.57
PDE5A O76074 1/20 0.56
PRKCZ Q05513 6/20 0.53
EGFR P00533 1/20 0.53
ERBB2 P04626 1/20 0.53
PTGS2 P35354 1/20 0.52
ATM Q13315 1/20 0.51
NR3C2 P08235 2/20 0.50
LMNA P02545 1/20 0.48
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
APC P25054 1/20 0.46
PGR P06401 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31574534 0.92 MEN1 (0.65) MEN1KMT2ANPSR1PDE5APRKCZ
SCHEMBL31574476 0.89 PTGS2 (0.64) MEN1KMT2ANPSR1PDE5APRKCZ
SCHEMBL31574490 0.87 KMT2A (0.61) MEN1KMT2ANPSR1PDE5APRKCZ
SCHEMBL31574520 0.86 LMNA (0.49) MEN1KMT2ANPSR1PDE5APRKCZ
SCHEMBL23052325 0.77 MEN1 (0.69) MEN1KMT2ANPSR1EGFRPTGS2
SCHEMBL31574511 0.74 KMT2A (0.59) MEN1KMT2ANPSR1EGFRLMNA
SCHEMBL31574604 0.74 KMT2A (0.59) MEN1KMT2ANPSR1EGFRLMNA
SCHEMBL31574522 0.74 MEN1 (0.59) MEN1KMT2ANPSR1L3MBTL1CYP1A2
SCHEMBL23052327 0.74 MEN1 (0.59) MEN1KMT2ANPSR1EGFRPTGS2
SCHEMBL31574551 0.74 MEN1 (0.51) MEN1KMT2ANPSR1PRKCZLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed