Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | DLAT | P10515 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351523 | 0.82 | ALOX5 (0.61) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL31576826 | 0.80 | ALOX5 (0.55) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL6275233 | 0.77 | ALOX5 (0.53) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL819253 | 0.75 | ALOX5 (0.78) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL8667736 | 0.74 | ALOX5 (0.69) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL12729054 | 0.74 | ALOX5 (0.73) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| Lupulone SCHEMBL2431439 | 0.73 | ALOX5 (0.67) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL31576812 | 0.71 | ALOX5 (0.64) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL6274814 | 0.71 | ALOX5 (0.44) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL6269718 | 0.71 | ALOX5 (0.44) | ALOX5KDM4EMEN1AKR1B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104281-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-05-22 | — | — | WO | disclosed |
| EP-4556004-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | Centre National de la Recherche Scientifique (FR) | 2025-05-21 | — | — | EP | disclosed |