Lupulone

Lupulone

SCHEMBL2431439

CC(C)=CCC1=C(O)C(C(=O)CC(C)C)=C(O)C(CC=C(C)C)(CC=C(C)C)C1=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ MEN1 O00255 2/20 0.67
▸ KMT2A Q03164 2/20 0.67
▸ AKR1B10 O60218 1/20 0.67
▸ CYP3A4 P08684 3/20 0.36
▸ PTGES O14684 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ SLC6A2 P23975 2/20 0.36
▸ SLC6A4 P31645 2/20 0.36
▸ SLC6A3 Q01959 2/20 0.36
▸ NR1I2 O75469 1/20 0.36
▸ DLAT P10515 1/20 0.36
▸ SIRT2 Q8IXJ6 1/20 0.36
▸ SIRT1 Q96EB6 1/20 0.36
▸ ACHE P22303 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819253 0.88 ALOX5 (0.78) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL29420850 0.86 ALOX5 (0.80) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL29420849 0.86 ALOX5 (0.80) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL17584889 0.86 ALOX5 (0.80) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL18324946 0.84 ALOX5 (0.48) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL31576826 0.82 ALOX5 (0.55) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL8667736 0.81 ALOX5 (0.69) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL9773779 0.80 ALOX5 (1.00) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL6125218 0.80 ALOX5 (1.00) ALOX5KDM4EMEN1KMT2AAKR1B10
SCHEMBL144835 0.80 ALOX5 (1.00) ALOX5KDM4EMEN1KMT2AAKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102053-A1 FOAM ENHANCING PHOSPHOLIPID EMULSION SYSTEMS ABSTRAX TECH INC. (US) 2026-05-15 — — WO claimed
US-20260125625-A1 HOPS ACIDS STABILIZED EMULSIONS ABSTRAX TECH INC (US) 2026-05-07 — — US claimed
US-20260123653-A1 Foam Enhancing Phospholipid Emulsion Systems ABSTRAX TECH INC (US) 2026-05-07 — — US claimed
EP-4312981-B1 EDIBLE ORAL COMPOSITIONS COMPRISING HOPS PROCTER & GAMBLE (US) 2025-11-05 — — EP claimed
EP-4640205-A2 ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACID AND FLUORIDE The Procter & Gamble Company (US) 2025-10-29 — — EP claimed
EP-4623074-A1 RECOMBINANT POLYPEPTIDES WITH PRENYLTRANSFERASE ACTIVITY FOR BIOSYNTHESIS OF CANNABINOIDS AND HOP COMPOUNDS Epimeron USA, Inc. (US) 2025-10-01 — — EP claimed
US-20250295565-A1 Oral Care Compositions Comprising Hops Beta Acids And Fluoride Ions PROCTER & GAMBLE (US) 2025-09-25 — — US claimed
US-20250270598-A1 RECOMBINANT POLYPEPTIDES WITH PRENYLTRANSFERASE ACTIVITY FOR BIOSYNTHESIS OF CANNABINOIDS AND HOP COMPOUNDS EPIMERON USA, INC. (US) 2025-08-28 — — US claimed
US-20250262262-A1 a-ACID AND/OR B-ACID BASED COPOSITIONS FROM HUMULUS FOR USE IN A HUMAN AND/OR VETERINARY APPLICATION OROTECH NV (BE) 2025-08-21 — — US claimed
EP-4037765-B1 ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACID AND AMINO ACID PROCTER & GAMBLE (US) 2025-08-20 — — EP claimed
WO-2008058694-A1 EXTRACTION METHOD FOR THE CLASSIFIED EXTRACTION AND SEPARATION OF VEGETABLE COMPONENT MATERIALS, AND THE APPLICATION THEREOF ASLIEH NOOKANDEH-BAUMGAERTNER (DE) 2008-05-22 — — WO claimed
EP-1920777-A1 Extraction method for the fractioned preparation and separation of plant ingredients and use thereof Nookandeh-Baumgärtner, Aslieh, Dr. (DE) 2008-05-14 — — EP claimed
EP-1240821-B1 Animal litter GIMBORN GMBH H VON (DE) 2007-01-17 — — EP claimed
EP-1200053-B1 STABLE HYDROGENATED LUPULONE ANTIBACTERIAL ORAL COMPOSITIONS COLGATE PALMOLIVE CO (US) 2005-12-21 — — EP claimed
EP-0931542-B1 Cosmetic composition containing phloroglucinol OREAL (FR) 2004-01-14 — — EP claimed
EP-1185237-B1 SYNERGISTIC ANTIBACTERIAL COMBINATION COLGATE PALMOLIVE CO (US) 2003-09-03 — — EP claimed
EP-1240821-A2 Animal litter SÜD-CHEMIE AG (DE) 2002-09-18 — — EP claimed
US-6054137-A A THERAPEUTIC TREATMENT FOR STIMULATING PROLIFERATION OF HUMAN KERATINOCYTES AND FOR SKIN DISORDERS SOCIETE L'OREAL S.A. (FR) 2000-04-25 — — US claimed
EP-0901455-A1 PROCESS FOR THE CATALYTIC HYDROGENATION OF TERPENOIDS NIGU CHEMIE GMBH (DE) 1999-03-17 — — EP claimed
WO-1997044304-A1 PROCESS FOR THE CATALYTIC HYDROGENATION OF TERPENOIDS NIGU CHEMIE GMBH (DE) 1997-11-27 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295565-A1 Oral Care Compositions Comprising Hops Beta Acids And Fluoride Ions HAX1, AP3S1, AFF1 ALOX5 4473/4885KDM4E 4723/4885MEN1 2268/4885
US-20260125625-A1 HOPS ACIDS STABILIZED EMULSIONS HAO2, NIPSNAP1, AP2S1 ALOX5 1575/4885KDM4E 4861/4885MEN1 3371/4885
US-20260123653-A1 Foam Enhancing Phospholipid Emulsion Systems PHOSPHO1, PLTP, PLIN3 ALOX5 165/4885KDM4E 1930/4885MEN1 1095/4885
US-20250262262-A1 a-ACID AND/OR B-ACID BASED COPOSITIONS FROM HUMULUS FOR USE IN A HUMAN AND/OR VETERINARY APPLICATION CYP8B1, HMBS, HPD ALOX5 339/4885KDM4E 1425/4885MEN1 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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