Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153878 | 0.99 | CCR2 (0.50) | CCR2L3MBTL1KCNH2RXFP1CCR1 | |
| SCHEMBL3148147 | 0.98 | CCR2 (0.49) | CCR2L3MBTL1KCNH2RXFP1KMT2A | |
| SCHEMBL3148887 | 0.97 | CCR2 (0.53) | CCR2L3MBTL1KCNH2RXFP1CCR1 | |
| SCHEMBL3149703 | 0.96 | CCR2 (0.51) | CCR2L3MBTL1KCNH2RXFP1CCR1 | |
| SCHEMBL3148157 | 0.92 | GAA (0.46) | CCR2L3MBTL1RXFP1KMT2A | |
| SCHEMBL3154679 | 0.92 | GAA (0.49) | CCR2L3MBTL1CCR1KMT2A | |
| SCHEMBL3158340 | 0.90 | CACNA1H (0.44) | CCR2L3MBTL1CCR1KMT2A | |
| SCHEMBL3145106 | 0.89 | F10 (0.49) | CCR2L3MBTL1RXFP1CCR1KMT2A | |
| SCHEMBL3148378 | 0.89 | GAA (0.49) | CCR2L3MBTL1CCR1KMT2A | |
| SCHEMBL3273918 | 0.89 | CCR2 (0.55) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-B1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-06-19 | — | — | EP | disclosed |
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, TRPV1 | CCR2 417/4885L3MBTL1 3132/4885KCNH2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.