SCHEMBL31578293

SCHEMBL31578293

Cn1cnnc1CC1(c2cccc(NC(=O)c3cc(CNC4CCCCC4)c4c(n3)C(C)(C)CO4)c2)CC(C#N)C1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.62
▸ CBL P22681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25360442 0.89 CBLB (0.61) CBLBCBL
SCHEMBL25358972 0.89 CBLB (0.62) CBLBCBL
SCHEMBL31115405 0.86 CBLB (0.60) CBLB
SCHEMBL25360512 0.86 CBLB (0.60) CBLB
SCHEMBL31578380 0.85 CBLB (0.66) CBLBCBL
SCHEMBL30625466 0.83 CBLB (0.52) CBLB
SCHEMBL30625557 0.83 CBLB (0.52) CBLB
SCHEMBL30625569 0.83 CBLB (0.52) CBLB
SCHEMBL30625489 0.83 CBLB (0.59) CBLBCBL
SCHEMBL30625610 0.83 CBLB (0.52) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163047-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE, LTD. (KY) 2025-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163047-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH NFATC1, GZMB, IFNG CBLB 2362/4885CBL 2661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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