Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 19/20 | 0.46 |
| ▸ | CBLC | Q9ULV8 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CBL | P22681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578363 | 0.90 | CBLB (0.47) | CBLBCBLCCBL | |
| SCHEMBL31578283 | 0.87 | CBLB (0.47) | CBLBCBLCCBL | |
| SCHEMBL31578187 | 0.84 | CBLB (0.51) | CBLBCBLCNTRK1CBL | |
| SCHEMBL31578232 | 0.83 | CBLB (0.44) | CBLBCBLCCBL | |
| SCHEMBL31578222 | 0.81 | CBLB (0.58) | CBLBCBLCCBL | |
| SCHEMBL31115368 | 0.80 | CBLB (0.52) | CBLBCBLCNTRK1CBL | |
| SCHEMBL31578234 | 0.76 | CBLB (0.61) | CBLBCBLCCBL | |
| SCHEMBL31578263 | 0.76 | CBLB (0.57) | CBLBCBLCCBL | |
| SCHEMBL25356270 | 0.75 | CBLB (0.47) | CBLBCBLCCBL | |
| SCHEMBL31578336 | 0.75 | CBLB (0.49) | CBLBCBLCNTRK1CBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163047-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE, LTD. (KY) | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163047-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | NFATC1, GZMB, IFNG | CBLB 2362/4885CBLC 2283/4885NTRK1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.