Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.53 |
| ▸ | WNT3A | P56704 | 7/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409208 | 0.83 | ROCK2 (0.58) | CTNNB1WNT3AROCK2ROCK1CYP2D6 | |
| SCHEMBL5407632 | 0.80 | CTNNB1 (0.54) | CTNNB1WNT3AROCK2ROCK1CYP2D6 | |
| SCHEMBL5413397 | 0.79 | MAOB (0.56) | CTNNB1WNT3AROCK2ROCK1HRH4 | |
| SCHEMBL3637193 | 0.78 | CTNNB1 (0.52) | CTNNB1WNT3AROCK2ROCK1MAOB | |
| SCHEMBL5415090 | 0.77 | HPGD (0.58) | CTNNB1WNT3AROCK2ROCK1MAOB | |
| SCHEMBL15223911 | 0.75 | HRH4 (0.63) | HRH4 | |
| SCHEMBL122504 | 0.75 | ROCK2 (0.64) | CTNNB1WNT3AROCK2ROCK1MAOB | |
| SCHEMBL29521387 | 0.75 | ROCK2 (0.64) | CTNNB1WNT3AROCK2ROCK1MAOB | |
| SCHEMBL4404815 | 0.74 | CTNNB1 (0.69) | CTNNB1WNT3AROCK2ROCK1CYP2D6 | |
| SCHEMBL3502643 | 0.73 | L3MBTL1 (0.47) | CTNNB1WNT3AROCK2HRH4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | disclosed |