Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31581627 | 0.84 | HCRTR1 (0.46) | HCRTR1PTGDR2HCRTR2CCNKCDK12 | |
| SCHEMBL26120478 | 0.79 | CCNK (0.47) | HCRTR1PTGDR2HCRTR2CCNKCDK12 | |
| SCHEMBL25533413 | 0.77 | USP30 (0.40) | PTGDR2CCNKCDK12 | |
| SCHEMBL25234548 | 0.77 | USP30 (0.40) | PTGDR2CCNKCDK12 | |
| Trifluoroacetic Acid SCHEMBL30915024 | 0.76 | HRH4 (0.49) | HCRTR1PTGDR2CCNKCDK12HDAC3 | |
| SCHEMBL18607391 | 0.75 | ULK1 (0.55) | HCRTR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27233778 | 0.75 | CDK12 (0.56) | HCRTR1PTGDR2HSD11B1CCNKCDK12 | |
| SCHEMBL27233705 | 0.75 | CDK12 (0.56) | HCRTR1PTGDR2HSD11B1CCNKCDK12 | |
| SCHEMBL27233710 | 0.75 | CDK12 (0.56) | HCRTR1PTGDR2HSD11B1CCNKCDK12 | |
| SCHEMBL26126794 | 0.73 | IDH2 (0.40) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025103475-A1 | HETEROCYCLIC CARBONYL DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-05-22 | — | — | WO | disclosed |