Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31581995

CCCNCCCCCNCCCCCCCCCCCCCCCN.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.56
PAOX Q6QHF9 4/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CA12 O43570 3/20 0.43
CA2 P00918 3/20 0.43
CA4 P22748 3/20 0.43
CA6 P23280 3/20 0.43
CA5A P35218 3/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
CA5B Q9Y2D0 3/20 0.43
CA3 P07451 2/20 0.43
F13A1 P00488 2/20 0.43
CYP1A2 P05177 2/20 0.43
ALOX15 P16050 2/20 0.43
THPO P40225 2/20 0.43
CA1 P00915 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31581884 1.00 HDAC6 (0.56) HDAC6PAOXMAOAMAOBCA12
Trifluoroacetic Acid SCHEMBL8501095 0.88 HDAC6 (0.58) HDAC6PAOXCA12CA2CA4
Spermine SCHEMBL3134527 0.85 HDAC6 (0.67) HDAC6PAOXMAOAMAOBCA12
Spermine SCHEMBL674873 0.85 HDAC6 (0.67) HDAC6PAOXMAOAMAOBCA12
Trifluoroacetic Acid SCHEMBL5344960 0.83 PAOX (0.45) PAOXCA12CA2CA4CA6
Trifluoroacetic Acid SCHEMBL5548189 0.82 HDAC6 (0.54) HDAC6PAOXMAOAMAOBCA12
Dodecylamine SCHEMBL23001137 0.81 DNM1 (0.56) CYP1A2TSHREPHX1MEN1KMT2A
Decylamine SCHEMBL28610774 0.81 DNM1 (0.56) CYP1A2TSHREPHX1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL28868688 0.81 DNM1 (0.56) CYP1A2TSHREPHX1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL29282412 0.81 DNM1 (0.56) CYP1A2TSHREPHX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106386-A1 A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed