Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8501095

CCCCCCCCNCCCNCCCCNCCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.58
RELA Q04206 4/20 0.53
EPHX1 P07099 1/20 0.50
PAOX Q6QHF9 1/20 0.50
S1PR1 P21453 6/20 0.45
S1PR3 Q99500 6/20 0.45
S1PR2 O95136 5/20 0.45
S1PR5 Q9H228 3/20 0.45
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
CA3 P07451 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5540177 0.88 HDAC6 (0.50) HDAC6RELAEPHX1PAOXS1PR1
Trifluoroacetic Acid SCHEMBL31581995 0.88 HDAC6 (0.56) HDAC6EPHX1PAOXS1PR1S1PR3
Trifluoroacetic Acid SCHEMBL31581884 0.88 HDAC6 (0.56) HDAC6EPHX1PAOXS1PR1S1PR3
Trifluoroacetic Acid SCHEMBL9443023 0.88 HDAC6 (0.53) HDAC6RELAEPHX1PAOXS1PR1
Spermine SCHEMBL674873 0.88 HDAC6 (0.67) HDAC6PAOXCA12CA2CA4
Spermine SCHEMBL3134527 0.88 HDAC6 (0.67) HDAC6PAOXCA12CA2CA4
Acetic Acid SCHEMBL134140 0.84 PAOX (0.63) HDAC6RELAPAOXS1PR1S1PR3
Hexadecylamine SCHEMBL23001148 0.84 DNM1 (0.56) EPHX1ALDH1A1TSHRMEN1CYP1A2
Decylamine SCHEMBL28610774 0.84 DNM1 (0.56) EPHX1ALDH1A1TSHRMEN1CYP1A2
Trifluoroacetic Acid SCHEMBL30275947 0.84 DNM1 (0.56) EPHX1ALDH1A1TSHRMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789708-A4 MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS APOLLON INC (US) 1999-12-29 EP disclosed
EP-0789708-A1 MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS APOLLON, INC. (US) 1997-08-20 EP disclosed