Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315915 | 0.94 | GHSR (0.63) | GHSRKMT2AALDH1A1MAPTABCB11 | |
| Hydrochloric Acid SCHEMBL317007 | 0.94 | GHSR (0.62) | GHSRKMT2AALDH1A1MAPTABCB11 | |
| SCHEMBL315788 | 0.92 | POLB (0.55) | GHSRPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL315547 | 0.89 | GHSR (0.58) | GHSRPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL315884 | 0.88 | KMT2A (0.70) | GHSRKMT2AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL314995 | 0.88 | GHSR (0.57) | GHSRPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL316299 | 0.85 | KMT2A (0.57) | GHSRPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL315885 | 0.85 | OPRM1 (0.51) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL315615 | 0.84 | KMT2A (0.62) | GHSRKMT2AALDH1A1MAPTGPBAR1 | |
| Hydrochloric Acid SCHEMBL317416 | 0.84 | OPRM1 (0.53) | POLBSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093272-B2 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2012-01-10 | — | — | US | claimed |
| US-8093272-B2 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2012-01-10 | — | — | US | disclosed |