Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26596976 | 0.79 | CYP3A4 (0.34) | CYP11B1CYP11B2MAPK1LMNASMN1; SMN2 | |
| SCHEMBL2383365 | 0.76 | NOS1 (0.37) | NOS1LMNASMN1; SMN2MEN1NPC1 | |
| SCHEMBL28268432 | 0.72 | PARP1 (0.46) | — | |
| SCHEMBL29122301 | 0.72 | BACE1 (0.37) | NOS1LMNASMN1; SMN2MEN1NPC1 | |
| SCHEMBL31130304 | 0.71 | GRM2 (0.44) | NOS1MAPK1MEN1NPC1KMT2A | |
| SCHEMBL4083412 | 0.71 | NOS1 (0.34) | NOS1MAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10050859 | 0.69 | RECQL (0.43) | CYP11B1CYP11B2LMNASMN1; SMN2MEN1 | |
| SCHEMBL30449976 | 0.69 | RECQL (0.43) | CYP11B1CYP11B2LMNASMN1; SMN2MEN1 | |
| SCHEMBL25287629 | 0.69 | ELANE (0.41) | CYP11B2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL31582626 | 0.68 | MAPK1 (0.37) | MAPK1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |