Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 3/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142963 | 0.82 | NOS1 (0.34) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL30848040 | 0.82 | NOS1 (0.34) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL23308487 | 0.79 | GABRA1 (0.36) | MAPK1LMNAGLABRD4CREBBP | |
| SCHEMBL20665049 | 0.79 | ADRA2A (0.41) | NOS1MAPK1ADRA2A | |
| SCHEMBL2383365 | 0.76 | NOS1 (0.37) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL15808281 | 0.75 | PDE1A (0.40) | MAPK1L3MBTL1NPC1GLARAB9A | |
| SCHEMBL28920149 | 0.74 | GAA (0.34) | MAPK1BACE1 | |
| SCHEMBL25240140 | 0.73 | NQO2 (0.36) | MAPK1NPC1RAB9APDE1APDE1B | |
| SCHEMBL31750476 | 0.72 | HTR2A (0.43) | MAPK1PDE1C | |
| SCHEMBL29122301 | 0.72 | BACE1 (0.37) | NOS1MEN1NPC1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2014092104-A1 | OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL USE OF SAME | 大日本住友製薬株式会社 (JP) | 2014-06-19 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |