SCHEMBL31584033

SCHEMBL31584033

CC(C)(C)OC(=O)N1CCC(c2cc3onc(N4CCC(=O)NC4=O)c3cc2F)CC1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ DDB1 Q16531 6/20 0.42
▸ CRBN Q96SW2 6/20 0.42
▸ GPR119 Q8TDV5 11/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27168084 0.85 DDB1 (0.50) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL24881549 0.84 DDB1 (0.46) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL31583510 0.82 GPR119 (0.45) KDM4EMAPTTHRBGPR119SMN1; SMN2
SCHEMBL29930514 0.80 DDB1 (0.41) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL27031107 0.80 DDB1 (0.41) KDM4EMAPTTHRBDDB1CRBN
Formic Acid SCHEMBL31583332 0.78 CRBN (0.32) DDB1CRBN
SCHEMBL31333939 0.78 DDB1 (0.42) KDM4EMAPTTHRBDDB1CRBN
SCHEMBL31134480 0.78 DDB1 (0.45) MAPTDDB1CRBNGPR119SMN1; SMN2
SCHEMBL29930726 0.77 DDB1 (0.39) DDB1CRBNGPR119
SCHEMBL27031216 0.77 DDB1 (0.39) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 — — WO disclosed
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