Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSE | P14091 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583380 | 0.82 | GPR119 (0.44) | USP30NR3C1GPR119OPRM1OPRD1 | |
| SCHEMBL10060693 | 0.80 | GPR119 (0.60) | USP30GPR119MAPT | |
| SCHEMBL30858274 | 0.79 | IRAK4 (0.37) | PRMT5WDR77 | |
| SCHEMBL30483040 | 0.78 | PRMT5 (0.45) | USP30PRMT5WDR77BACE1 | |
| SCHEMBL2355889 | 0.78 | PRMT5 (0.45) | USP30PRMT5WDR77BACE1 | |
| SCHEMBL2800381 | 0.76 | USP30 (0.44) | USP30NR3C1GPR119KDM4EMAPT | |
| SCHEMBL30186809 | 0.76 | USP30 (0.51) | USP30NR3C1GPR119PRMT5WDR77 | |
| SCHEMBL12471570 | 0.76 | USP30 (0.49) | USP30GPR119PRMT5WDR77KDM4E | |
| SCHEMBL23546390 | 0.75 | USP30 (0.45) | USP30NR3C1GPR119KDM4EMAPT | |
| SCHEMBL31583610 | 0.75 | USP30 (0.56) | USP30GPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106910-A1 | DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR | FLARE THERAPEUTICS INC. (US) | 2025-05-22 | — | — | WO | disclosed |