Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | MTOR | P42345 | 4/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398601 | 0.84 | USP30 (0.46) | USP30GPR119PIK3CAMTORPIK3CG | |
| SCHEMBL30398620 | 0.84 | USP30 (0.47) | USP30GPR119PRMT5WDR77CTSD | |
| SCHEMBL28923309 | 0.81 | GPR119 (0.52) | USP30GPR119PIK3CAMTORPIK3CG | |
| SCHEMBL25151025 | 0.81 | IDO1 (0.38) | PRMT5WDR77 | |
| SCHEMBL14636611 | 0.79 | GPR119 (0.53) | GPR119PIK3CAMTORPIK3CGATR | |
| SCHEMBL30186853 | 0.79 | USP30 (0.49) | USP30GPR119PRMT5WDR77NR3C1 | |
| SCHEMBL10060693 | 0.78 | GPR119 (0.60) | USP30GPR119 | |
| SCHEMBL12471570 | 0.77 | USP30 (0.49) | USP30GPR119PRMT5WDR77CTSD | |
| SCHEMBL1359746 | 0.77 | USP30 (0.49) | USP30GPR119PIK3CAMTORPIK3CG | |
| SCHEMBL31584093 | 0.76 | USP30 (0.46) | USP30GPR119PRMT5WDR77PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132646-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |