Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584932 | 0.78 | EPHX2 (0.35) | PGRPDK2PDK4PDK1PDK3 | |
| SCHEMBL25316575 | 0.72 | BACE1 (0.35) | PGR | |
| SCHEMBL31178347 | 0.72 | BACE1 (0.35) | PGR | |
| SCHEMBL26025816 | 0.70 | HTR7 (0.35) | HTR6 | |
| SCHEMBL24690863 | 0.70 | PDK2 (0.40) | PGRPDK2PDK4PDK1PDK3 | |
| SCHEMBL25900302 | 0.70 | CYP2D6 (0.36) | PGRAKR1B1KMT2A | |
| SCHEMBL24690663 | 0.68 | PDK2 (0.38) | PGRPDK2PDK4PDK1PDK3 | |
| SCHEMBL31116993 | 0.68 | PDK2 (0.38) | PGRPDK2PDK4PDK1PDK3 | |
| SCHEMBL1722012 | 0.67 | PGR (0.69) | PGRPDK2PDK4ATAD2AKR1B1 | |
| SCHEMBL24690866 | 0.67 | EPHX2 (0.40) | PGRPDK2PDK4PDK1PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106863-A1 | LACTAM DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-05-22 | — | — | WO | disclosed |