Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21195976 | 0.85 | RXRA (0.46) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL21198430 | 0.85 | ALDH1A1 (0.45) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL20132934 | 0.85 | ALDH1A1 (0.45) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL19949097 | 0.85 | RXRA (0.43) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL17681723 | 0.85 | RXRA (0.43) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL31105959 | 0.85 | ALDH1A1 (0.45) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL21263636 | 0.85 | RXRA (0.43) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL24373169 | 0.82 | RXRA (0.42) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL29478967 | 0.82 | RXRA (0.42) | LMNAALDH1A1POLBRXRARXRB | |
| SCHEMBL5409241 | 0.82 | ALDH1A1 (0.45) | LMNAALDH1A1POLBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106014-A1 | COMPOUNDS AND METHODS FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2025-05-22 | — | — | WO | disclosed |