Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850705 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL31588227 | 0.86 | GAA (0.41) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL23851980 | 0.86 | GAA (0.41) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL26143861 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL10278266 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1GAANR4A1MAPT | |
| SCHEMBL29748980 | 0.81 | TNIK (0.44) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL26143864 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL28799312 | 0.81 | TNIK (0.44) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL3085427 | 0.81 | S100B (0.59) | KDM4EALDH1A1GAAPOLBNR4A1 | |
| SCHEMBL13354909 | 0.80 | DRD2 (0.53) | KDM4EALDH1A1MAPTSMN1; SMN2S100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |