Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.42 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587686 | 0.88 | NOTUM (0.46) | NOTUMLMNATP53ARTSHR | |
| SCHEMBL31587169 | 0.85 | AR (0.47) | ARHSD17B10PTGS1AKR1C3AKR1C2 | |
| SCHEMBL1321573 | 0.83 | MEN1 (0.59) | NOTUMARHSD17B10TSHRMAPT | |
| SCHEMBL31586911 | 0.82 | POLB (0.54) | NOTUMLMNAMAPTMEN1KMT2A | |
| SCHEMBL15603510 | 0.81 | HDAC3 (0.55) | LMNAHSD17B10TSHRMAPT | |
| SCHEMBL31587913 | 0.81 | KDM4E (0.46) | NOTUMARMEN1KMT2A | |
| SCHEMBL23023945 | 0.79 | LMNA (0.51) | NOTUMLMNATP53MEN1KMT2A | |
| SCHEMBL31587512 | 0.78 | RXRA (0.43) | AR | |
| SCHEMBL15352892 | 0.75 | NOTUM (0.55) | NOTUMLMNAMAPK1HSD17B10TSHR | |
| SCHEMBL30264186 | 0.75 | NOTUM (0.55) | NOTUMLMNAMAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |