Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417822 | 1.00 | POLB (0.42) | POLBNR4A2KMT2AMPOBCHE | |
| SCHEMBL11346258 | 0.88 | ALDH1A1 (0.39) | KMT2AMPOBCHEACHEMAPT | |
| SCHEMBL27753764 | 0.87 | POLB (0.40) | POLBNR4A2KMT2AMPOBCHE | |
| SCHEMBL2419272 | 0.82 | POLB (0.44) | POLBNR4A2KMT2AMPOBCHE | |
| SCHEMBL8127677 | 0.78 | POLB (0.47) | POLBNR4A2KMT2AMPOBCHE | |
| SCHEMBL11341944 | 0.77 | ELANE (0.42) | POLBKMT2AACHECHRM1MAPT | |
| SCHEMBL8936165 | 0.76 | POLB (0.42) | POLBNR4A2KMT2AACHECHRM1 | |
| SCHEMBL31590436 | 0.72 | MOK (0.58) | POLBKMT2AMAPTHTTLMNA | |
| SCHEMBL31716536 | 0.71 | ALDH1A1 (0.51) | POLBKMT2AHPGDCASP1SMN1; SMN2 | |
| SCHEMBL11347720 | 0.70 | KDM4E (0.40) | NR4A2MPOBCHEACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051459-A | Quinoline compounds as modulators of RAGE activity and uses thereof | 纽约大学 | 2025-05-27 | — | — | CN | disclosed |