Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490198 | 0.83 | LMNA (0.44) | TDP1LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL8075340 | 0.82 | TDP1 (0.48) | TDP1LMNAL3MBTL1PDE4ATRPA1 | |
| SCHEMBL5873439 | 0.80 | TDP1 (0.50) | TDP1LMNAL3MBTL1PDE4ASLC6A2 | |
| SCHEMBL27825950 | 0.80 | TDP1 (0.50) | TDP1LMNAL3MBTL1PDE4ASLC6A2 | |
| SCHEMBL4077892 | 0.80 | TDP1 (0.50) | TDP1LMNAL3MBTL1PDE4ASLC6A2 | |
| Mannitol SCHEMBL27535805 | 0.76 | TSHR (0.58) | TDP1LMNAL3MBTL1PDE4ATRPA1 | |
| Alcohol SCHEMBL28032136 | 0.76 | AOC3 (0.46) | TDP1LMNAL3MBTL1TRPA1SLC6A2 | |
| SCHEMBL550791 | 0.75 | AOC3 (0.48) | TDP1LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL550790 | 0.75 | AOC3 (0.48) | TDP1LMNAL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL551822 | 0.75 | AOC3 (0.48) | TDP1LMNAL3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036901-B1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-01 | — | — | EP | claimed |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | claimed |
| CN-101611023-A | The 1-phenyl 1-thio-D-glucitol derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-23 | — | — | CN | claimed |
| EP-2103607-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-09-23 | — | — | EP | claimed |
| EP-2952206-B1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-10-24 | — | — | EP | disclosed |
| US-10022389-B2 | Prophylactic or therapeutic drug for constipation | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20150374735-A1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2952206-A1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| JP-2010018611-A | PREVENTIVE OR THERAPEUTIC AGENT FOR DIABETES, DIABETES-RELATED DISEASES OR DIABETIC COMPLICATIONS CONTAINING 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE AS EFFECTIVE INGREDIENT | TAISHO PHARMACEUTICAL CO LTD | 2010-01-28 | — | — | JP | disclosed |
| CN-101611023-A | The 1-phenyl 1-thio-D-glucitol derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |
| CN-101611023-A | The 1-phenyl 1-thio-D-glucitol derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |
| CN-101611023-A | The 1-phenyl 1-thio-D-glucitol derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |
| EP-2103607-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-2103607-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008072726-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008001864-A1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374735-A1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION | SLC5A1, SLC5A2, SLC10A2 | TDP1 4114/4885LMNA 3968/4885L3MBTL1 3885/4885 |
| US-10022389-B2 | Prophylactic or therapeutic drug for constipation | SLC5A1, SLC5A2, SLC10A2 | TDP1 4114/4885LMNA 3968/4885L3MBTL1 3885/4885 |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | TDP1 1126/4885LMNA 4603/4885L3MBTL1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.