Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 10/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739054 | 0.84 | GRM2 (0.45) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL31591060 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL27286166 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL17696410 | 0.79 | KLKB1 (0.55) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL30739125 | 0.79 | KLKB1 (0.53) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL31591066 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL31591079 | 0.78 | KLKB1 (0.44) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL31591075 | 0.78 | KLKB1 (0.52) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL31591076 | 0.77 | KLKB1 (0.51) | KDM4EALDH1A1LMNAKLKB1KLK1 | |
| SCHEMBL30739124 | 0.77 | KLKB1 (0.54) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |