Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.52 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739125 | 0.94 | KLKB1 (0.53) | KLKB1ITKCYP19A1SCDEGLN2 | |
| SCHEMBL31591059 | 0.88 | KLKB1 (0.52) | KLKB1ITKSCDERCC5ALKBH1 | |
| SCHEMBL31591068 | 0.84 | KLKB1 (0.45) | KLKB1ITKCYP19A1SCDEGLN2 | |
| SCHEMBL30730357 | 0.84 | HSD17B10 (0.57) | KLKB1ITKCYP19A1SCDEGLN2 | |
| SCHEMBL31591060 | 0.83 | KDM4E (0.49) | KLKB1KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL27364042 | 0.83 | KLKB1 (0.54) | KLKB1ITKCYP19A1SCDKDM4E | |
| SCHEMBL31591078 | 0.82 | KLKB1 (0.43) | KLKB1ITKSCDEGLN2KDM4E | |
| SCHEMBL30739056 | 0.82 | KLKB1 (0.50) | KLKB1ITKCYP19A1SCDALDH1A1 | |
| SCHEMBL30739106 | 0.81 | KLKB1 (0.73) | KLKB1ITKEGLN2 | |
| SCHEMBL31591066 | 0.81 | KDM4E (0.44) | KLKB1KDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |