Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730357 | 0.87 | HSD17B10 (0.57) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL19300037 | 0.84 | HSD17B10 (0.51) | KLKB1HSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL30739125 | 0.84 | KLKB1 (0.53) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL20529831 | 0.83 | KLKB1 (0.52) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL31591075 | 0.83 | KLKB1 (0.52) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL27364232 | 0.82 | KLKB1 (0.53) | KLKB1HSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL17229366 | 0.82 | KLKB1 (0.51) | KLKB1HSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL30739156 | 0.81 | KLKB1 (0.51) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL30739164 | 0.81 | KLKB1 (0.51) | KLKB1CYP19A1ITKSCDCYP11B1 | |
| SCHEMBL752774 | 0.81 | LMNA (0.61) | KLKB1HSD17B10ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |