Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | SLC9A2 | Q9UBY0 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | JAK1 | P23458 | 4/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591105 | 0.83 | TSHR (0.43) | TSHRALDH1A1NPC1LMNA | |
| SCHEMBL30739016 | 0.83 | LMNA (0.52) | ALDH1A1NPC1LMNAKMT2AGAA | |
| SCHEMBL30739114 | 0.82 | KLKB1 (0.46) | — | |
| SCHEMBL31591085 | 0.75 | TSHR (0.46) | TSHRALDH1A1NPC1LMNACYP11B2 | |
| SCHEMBL30739065 | 0.69 | LMNA (0.48) | ALDH1A1NPC1LMNAKMT2AGAA | |
| SCHEMBL30739051 | 0.68 | KLKB1 (0.43) | LMNA | |
| SCHEMBL31591060 | 0.67 | KDM4E (0.49) | ALDH1A1LMNAKMT2A | |
| SCHEMBL30739420 | 0.67 | NPC1 (0.40) | TSHRALDH1A1NPC1LMNACYP11B2 | |
| SCHEMBL10373426 | 0.65 | TSHR (0.61) | TSHRALDH1A1NPC1LMNASLC2A1 | |
| SCHEMBL31591120 | 0.64 | TSHR (0.47) | TSHRALDH1A1NPC1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |