Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739420 | 0.89 | NPC1 (0.40) | TSHRNPC1LMNAALDH1A1KMT2A | |
| SCHEMBL31591061 | 0.84 | TSHR (0.43) | TSHRNPC1LMNAALDH1A1SLC2A1 | |
| SCHEMBL31591077 | 0.83 | TSHR (0.48) | TSHRNPC1LMNAALDH1A1KMT2A | |
| SCHEMBL30739113 | 0.81 | KLKB1 (0.45) | NPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL30739167 | 0.78 | KLKB1 (0.37) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31591089 | 0.75 | TSHR (0.47) | TSHRNPC1LMNAALDH1A1SLC2A1 | |
| SCHEMBL30739026 | 0.74 | CACNA1H (0.38) | TSHRNPC1LMNAALDH1A1KMT2A | |
| SCHEMBL370914 | 0.73 | NPBWR1 (0.48) | NPC1LMNACYP11B1CYP11B2NPBWR1 | |
| SCHEMBL369444 | 0.73 | NPBWR1 (0.48) | NPC1ALDH1A1SMN1; SMN2RAB9ANPBWR1 | |
| SCHEMBL369974 | 0.73 | NPBWR1 (0.48) | NPC1LMNAALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |