SCHEMBL31591664

SCHEMBL31591664

O=CCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.56
▸ TP53 P04637 3/20 0.56
▸ CASP3 P42574 2/20 0.53
▸ TLR2 O60603 2/20 0.53
▸ MDM2 Q00987 6/20 0.52
▸ KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8249262 1.00 MDM4 (0.56) MDM4TP53CASP3TLR2MDM2
SCHEMBL31192250 0.93 MDM2 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL31037162 0.89 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL20876850 0.89 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL30759499 0.89 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL13662312 0.89 CASP3 (0.50) MDM4TP53CASP3TLR2MDM2
SCHEMBL15586337 0.89 MDM4 (0.55) MDM4TP53CASP3TLR2MDM2
SCHEMBL28306730 0.88 MDM4 (0.54) MDM4TP53CASP3TLR2MDM2
SCHEMBL4553476 0.88 MDM4 (0.58) MDM4TP53CASP3MDM2KMT2A
SCHEMBL19927016 0.88 MDM4 (0.58) MDM4TP53CASP3MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2025-05-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF GLP1R, GIPR, GCGR MDM4 4740/4885TP53 3214/4885CASP3 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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