Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591664 | 1.00 | MDM4 (0.56) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL31192250 | 0.93 | MDM2 (0.55) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL31037162 | 0.89 | MDM4 (0.55) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL20876850 | 0.89 | MDM4 (0.55) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL30759499 | 0.89 | MDM4 (0.55) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL13662312 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL15586337 | 0.89 | MDM4 (0.55) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL28306730 | 0.88 | MDM4 (0.54) | MDM4TP53CASP3TLR2MDM2 | |
| SCHEMBL4553476 | 0.88 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL19927016 | 0.88 | MDM4 (0.58) | MDM4TP53CASP3MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |