⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465136 | 0.74 | — | — | |
| SCHEMBL9227462 | 0.73 | — | — | |
| SCHEMBL15549429 | 0.71 | LMNA (0.36) | — | |
| SCHEMBL12341103 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL31597365 | 0.68 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL4467770 | 0.67 | MEN1 (0.30) | — | |
| SCHEMBL15537578 | 0.66 | PDE10A (0.49) | — | |
| SCHEMBL2037658 | 0.65 | NR1H3 (0.58) | — | |
| SCHEMBL18046661 | 0.64 | HTT (0.33) | — | |
| SCHEMBL17541738 | 0.62 | KDM4C (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |