Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.72 |
| ▸ | CA1 | P00915 | 9/20 | 0.72 |
| ▸ | CA2 | P00918 | 9/20 | 0.72 |
| ▸ | CA9 | Q16790 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.57 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31597547 | 0.90 | CA12 (0.73) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31597397 | 0.82 | CA12 (0.70) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15231061 | 0.79 | CA12 (0.72) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18239992 | 0.79 | CA12 (0.70) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31597533 | 0.75 | PDE7A (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7477638 | 0.74 | DAO (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30103233 | 0.73 | PDE7A (1.00) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL844588 | 0.73 | PDE7A (1.00) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31597447 | 0.73 | PDE7A (0.70) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31597573 | 0.72 | CA12 (0.71) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058621-A | 2, 3-Dihydro quinazoline derivative containing substituted phenyl, preparation method and application thereof | 中国医学科学院药物研究所 | 2025-05-30 | — | — | CN | disclosed |